UNVEILING THE POWERHOUSE: ASCL1-DRIVEN SMALL CELL LUNG CANCER IS CHARACTERIZED BY HIGHER NUMBERS OF MITOCHONDRIA AND ENHANCED OXIDATIVE PHOSPHORYLATION

Abstract Background Small cell lung cancer (SCLC) is an aggressive malignancy with distinct molecular subtypes defined by transcription factors and inflammatory characteristics.This follow-up study aimed to validate the unique metabolic phenotype in achaete-scute homologue 1 (ASCL1)-driven SCLC cell lines and human tumor tissue.Methods Metabolic hi

Abstract Perceptual segregation of complex sounds such as speech and music simultaneously emanating from multiple sources is a remarkable ability that is common in humans and other animals alike.Unlike animal physiological experiments with simplified sounds click here or human investigations with spatially broad imaging techniques, this study combi

In recent years, it has become increasingly clear that space weather disturbances can be triggered by transient upstream mesoscale structures (TUMS), independently of the occurrence of large-scale solar wind (SW) structures, such as interplanetary coronal mass ejections and stream interaction regions.Different types of elbeco adu ripstop pants magn

Objective: Investigate the patterns of facial fractures presenting to an oral and maxillofacial service at a teaching hospital in Trinidad.Methods: A retrospective study was conducted to obtain information on traumatic maxillofacial and mandibular fractures from the Oral and Maxillofacial unit at the Eric Williams Medical Complex, Trinidad.Data was